If you’re wondering how to teach human body systems in a fun and engaging way, you’re in the right place! Human anatomy is such a fascinating topic, and it’s perfect for upper elementary and middle school students who are naturally curious about their bodies. But how do you keep them engaged while covering the circulatory system, digestive system, and more? I’ve gathered 10 fantastic activities and resources to help you make your human body systems unit both exciting and educational. Let’s dive in!
This blog post is designed with 5th grade NGSS standards in mind. It aligns to many state standards, including Florida!

1. How to Teach Human Body Systems: Reading Passages & Exit Slips
This resource is perfect for introducing each individual body system. It includes detailed passages on systems like the circulatory system, digestive system, nervous system, muscular system, respiratory system, skeletal system, immune system, excretory system, and urinary system.
For example, when introducing sensory organs, students get a comprehensive look at how their senses connect to various body systems as they read informational texts about their eyes, ears, tongue, nose, and skin.
The exit slips are a great way to check understanding at the end of the lesson, making it easy for both visual learners and small group discussions. This resource offers a fantastic way to engage students while covering key concepts of the human body systems unit.
2. How to Teach Human Body Systems: Hands-on Experiments and Labs
If you’re looking for a hands-on way to teach the nervous system, these reaction time experiments are a perfect fit. The labs help students explore how the brain and spinal cord work together to process information. There are three engaging experiments included in this resource:
- Reaction Time: Experiment #1 – Students test their reflexes with a ruler drop experiment. This is a great way to see how fast their nervous system reacts to visual stimuli.
- Reaction Time: Experiment #2 – Adding a blindfold, students will explore how removing visual input affects their reaction time.
- Reaction Time: Experiment #3 – This version adds even more challenges to the experiment, further deepening students’ understanding of sensory input and reflexes.
After completing each lab, students will record their data and answer reflection questions, which is a great way to promote critical thinking while studying the nervous system. These labs are fun, engaging, and offer a practical approach to understanding how the nervous system functions.
3. How to Teach Human Body Systems: Vocabulary Building
Learning the vocabulary related to human body systems is crucial for students to fully grasp how these systems function. Acquiring key terms helps them make connections between concepts, fostering a deeper understanding. This resource is a great way to introduce and reinforce the important vocabulary tied to the circulatory system. Students read an engaging informational text and use context clues to define essential terms such as heart, arteries, veins, and more.
By working through these vocabulary-building activities, students will better understand how blood circulates through the body and the role of each component in keeping the circulatory system functioning. This focus on vocabulary helps students enhance their comprehension of the overall human body systems unit, preparing them to tackle more complex ideas as they move forward.
4. How To Teach Human Body Systems: Creating Models
Building models of body systems is a great way to help students visualize how different parts of the body function together. For example, one activity focuses on creating a model of the lungs to demonstrate the process of breathing. Students can simulate the respiratory system with a few simple materials. Directions for building the model are included in this resource, as well as questions to help students understand the models they build.
This interactive way of teaching the respiratory system helps students understand the function of the lungs and reinforces the connection between the human body systems and real-life processes. Plus, it’s a fun activity that encourages visual learners to engage deeply with the science content.
5. How to Teach Human Body Systems: Sequencing Activities
For students who love hands-on activities, this resource is a great way to help them understand the digestive system through a fun sequencing activity. Students start by reading an informational passage about how the digestive system works, covering key concepts like the mouth, esophagus, stomach, small intestine, and large intestine.
After reading, they’ll cut out cards representing the different stages of the digestive process and arrange them in the correct order. This interactive way of learning helps students break down the complex steps of digestion into manageable parts, reinforcing their understanding of how food travels through the body.
By engaging with both the reading and the card activity, students solidify their grasp of the digestive system and how each organ contributes to the process. This activity also promotes critical thinking and is perfect for upper elementary students who need a visual and tactile way to grasp human body systems.
6. How to Teach Human Body Systems: Graphic Organizers
Graphic organizers are a great way to help students organize and visualize their knowledge of human body systems. This resource includes Venn diagrams and other organizers that allow students to compare and contrast systems, such as the skeletal system and muscular system.
For example, students can use a Venn diagram to identify how the skeletal system provides structure and protection, while the muscular system enables movement. In the overlapping section, they can note how both systems work together to support bodily functions, like how smooth muscle and bones contribute to posture and mobility.
These graphic organizers are excellent for visual learners who benefit from seeing how different body systems interact. This activity encourages students to think critically and make connections between individual systems while reinforcing key concepts in the human body systems unit.
7. How to Teach Human Body Systems: Interdisciplinary Writing in Science
Writing activities are a fantastic way to help students engage with the material in a creative and meaningful way. In this excretory system activity, students are asked to imagine they are traveling through the excretory system and write a story detailing their journey. The prompt encourages them to describe each phase of the system, including how the kidneys, ureters, bladder, and urethra work together to filter and remove waste from the body.
This writing activity allows students to dive deep into their understanding of the excretory system, using descriptive language to explain the process. It’s a great way to assess their comprehension of the human body systems while allowing them to express their knowledge creatively. This activity can be used as an individual assignment or in small groups for collaborative storytelling, making it a versatile addition to any science classroom.
8. How to Teach Human Body Systems: Comparing Plant and Animal Structures with Human Body Systems
Incorporating lessons on plant and animal structures is a great way to deepen students’ understanding of human body systems. By comparing different biological structures, students can see how various systems in animals and plants relate to the ones they’re studying in humans.
One activity that works well is reading the passage on Endoskeletons and Exoskeletons, where students learn about different skeletal structures in animals. After reading, they’ll complete a Venn diagram to compare and contrast endoskeletons (like the human skeletal system) with exoskeletons found in animals. This is a fun activity that helps students connect their knowledge of the human body with animal biology.
Another engaging option is the “Comparing Skin and Skin Coverings” passage, where students explore the similarities and differences between human skin and the coverings of various animals. They can fill in a chart with examples and notes, allowing for a more interactive exploration of these topics.
Finally, the “Structures of Plants and Humans” passage lets students compare plant structures with human body systems, further expanding their understanding of how organisms are built and function. These activities are ideal for students who love science and are curious about how the body works in relation to other living things.
9. Human Body Systems Review Game
A review game is a fun way to wrap up your human body systems unit and reinforce key concepts. This Human Body and Organs Concepts Review Game is designed to get students moving and thinking. Set up science stations around the room where students answer questions about the circulatory system, digestive system, nervous system, and other key systems.
Students can work in pairs or small groups to complete each station, discussing the functions of different body systems and answering questions about individual organs like the heart, lungs, and brain. This game is perfect for encouraging collaboration and promoting deeper understanding of the systems they’ve studied.
By using this interactive review, students can strengthen their recall of key concepts and prepare for assessments in a way that keeps them engaged and excited about learning.
10. Generation Genius Video: Human Body Systems
For a great introduction to the amazing body, Generation Genius offers an engaging video series on human body systems. It covers all the key concepts in an interactive way, perfect for upper elementary students who need a visual, high-energy explanation. This is a different way to approach your human body systems unit, and the videos are a hit in my science classroom. Check it out here.
LOOKING FOR AN ENTIRE UNIT OF HUMAN BODY SYSTEMS ACTIVITIES?
For a comprehensive approach to teaching human body systems, the Human Body Systems & Organs Unit bundle includes all the activities mentioned above, as well as a unit assessment to evaluate students’ understanding of key concepts. This bundle covers everything from hands-on activities and graphic organizers to engaging review games and writing prompts. With detailed passages, exit slips, and a variety of interactive tools, this resource is perfect for a complete human body systems unit. The included assessment helps ensure that students grasp important terms like red blood cells, arteries, and plasma, while also reinforcing how the different organ systems work together.
Now that you’ve got these 10 engaging activities in your toolbox, your students will be ready to dive deep into the different systems of the human body. Whether they’re learning about the circulatory system, nervous system, or digestive system, these resources offer a great way to challenge students, promote critical thinking, and bring some fun into your science classroom.
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